Open access
Sep 2026
Progressive behavioral and cognitive decline in Drosophila harboring AD-associated APOE4 variants
A scalable model to dissect APOE-dependent mechanisms and identify therapeutic targets in AD is established, establishing a scalable model of disease pathogenesis and highlighting a central role for oxidized lipid metabolism in AD.
S. Biglari, Eshani Yeragi, David Bamisaye et al.
· bioRxiv · 0 citations