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Review Open access Sep 2026

Characterization of a metabolomics signature of the brain-health-promoting MIND diet in older persons

Background The MIND diet supports healthy cognitive aging. Yet, a challenge remains to identify individuals who do not adhere to the MIND and could be at risk for accelerated cognitive decline. A multi-metabolite biomarker panel could facilitate population screening. Objectives To determine and validate a blood metabol...

Jeanne Neuffer, R. González-Domínguez, S. Lefèvre-Arbogast et al. · 0 citations
Open access Sep 2026

Pathway-specific polygenic risk scores reveal underlying mechanisms of cerebral small vessel disease

A validated WMH global-PRS is generated showing robust association with cSVD clinical complications and introduce a multi-cohort WMH ps-PRS framework that reveals candidate biological pathways with candidate biological associations across the lifespan and clinical outcomes.

T. D'Aoust, A. Tsuchida, C. Dufouil et al. · 0 citations

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