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C. Hou

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Open access Oct 2026

Thalamocortical dysconnectivity shapes cortical hierarchy disruption across illness durations in schizophrenia.

BACKGROUND Schizophrenia is increasingly conceptualized as a disorder of circuit-level dysfunction. However, how thalamocortical abnormalities differ across cohorts with varying illness durations and relate to large-scale cortical hierarchical organization remains unclear. METHODS We analyzed resting-state functional...

Huan Huang, LENA PALANIYAPPAN, He-Chun Li et al. · 0 citations
Open access Aug 2026

Distinctive subcortical connectivity predicts treatment response in first-episode schizophrenia.

A distinctive subcortical FC pattern dominated by the striatum was identified that was associated with overall treatment outcomes in first-episode schizophrenia and was positively correlated with the actual reduction in PANSS total scores following antipsychotic treatment.

C. Hou, Huan Huang, Si-Si Jiang et al. · 0 citations

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