Open access
Aug 2026
Smyca-FOXM1 ribonucleoprotein complex promotes homologous recombination and tumor immune evasion to define a therapeutic target of triple-negative breast cancer
This study identifies an unprecedented role of Smyca in HR repair to promote TNBC survival and immune evasion in response to therapy and suggests Smyca as a potential target for sensitizing TNBC to chemotherapy, PARPi, or immunotherapy.
Han Chen, Keng-Hao Chang, Sin-Rong Lee et al.
· Journal of Biomedical Scienc... · 0 citations