C. Jacoby

Oxyfunctionalization of Primary Benzylic C(sp3)–H Bonds with Water by a Molybdenum-Dependent Dehydrogenase

The selective oxyfunctionalization of C(sp3)–H bonds remains a central challenge in chemical synthesis. Although oxygenases and peroxygenases provide biocatalytic alternatives to metal-based chemical methods, their practical use is constrained by costly cofactor regeneration, toxic co-substrates, or limited selectivi...