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C. Kesserwan

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Open access Aug 2026

Distinct mutational landscapes for germline and somatic cancer variants in forty tumor suppressor genes

Germline and somatic cancer variants in tumor suppressor genes (TSGs) share loss of function mechanisms, but studies of a few genes (DICER1, CEBPA) demonstrated differences in variant consequence and location. To systematically assess whether TSGs display distinct mutational patterns we leveraged large public genetic d...

Suhasini D. Lulla, D. Ritter, C. Kesserwan et al. · 0 citations

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