Proton FLASH radiotherapy enhances control of triple-negative breast cancer through STING–IRF3 and CD8+ T-cell immunity
FLASH radiotherapy delivers radiation at ultra-high dose rates and has been demonstrated to spare normal tissue compared to standard radiotherapy, but it is not known if dose rate also modifies tumor response. Here we compare a single 13.5 Gy fraction of proton irradiation delivered at FLASH (F-PRT) or Standard (S-PRT)...