Review
Open access
Sep 2026
From mRNA stabilisation to mirror life: Biological orthogonality, incremental risk, and anticipatory governance
Molecular stabilisation of mRNA is central to the development of therapeutics. Stabilisation is gained through modifications that cause mRNA to resist degradation, evade immune recognition, and prolong expression. These modifications introduce degrees of biological orthogonality, which, in this context, is the extent t...
C. Lean, Russel M. Vincent, Kate E. Lynch et al.
· Frontiers in Bioengineering... · 0 citations