Author

C. Leiva-Sabadini

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Review Open access Sep 2026

From Biogenesis to Host Modulation: The Expanding Biology of Oral Streptococcal Membrane Vesicles.

Bacterial extracellular membrane vesicles (bEVs) provide fundamental biological functions through communication, ecological adaptation, and mediation of host interactions. Gram-positive oral streptococci were long considered to be incapable of bEVs production due to their thick peptidoglycan. In contrast, recent advanc...

S. Aguayo, C. Leiva-Sabadini, Paula Saavedra et al. · FEMS Microbiology Reviews · 0 citations

Open access Jul 2026

Quorum sensing rewires membrane vesicle protein cargo to promote antibiotic persistence in Streptococcus mutans

This study reveals that CSP QS coordinates biogenesis and selective cargo remodeling in S. mutans and identifies Pep299-containing vesicles as a quorum-regulated mechanism promoting antibiotic persistence and uncover a previously unrecognized connection between quorum sensing and vesicle-mediated persistence.

D. Dufour, C. Leiva-Sabadini, S. Aguayo et al. · Journal of Bacteriology · 0 citations