The asthma-obstructive sleep apnea overlap: pathophysiological links, clinical impact, and implications for integrated management
The asthma-obstructive sleep apnea (OSA) overlap is a clinically important phenotype, especially in patients with severe or difficult-to-control asthma. Rather than a simple coexistence of independent conditions, this overlap represents a distinct clinical entity modulated by shared pathobiological pathways. This revie...