Open access
Aug 2026
Design and Evaluation of PLGA-Based Hybrid Nanoparticles for Nasal Paclitaxel Delivery: Formulation Optimization, Barrier Transport, and Cytotoxicity Assessment
HNP–PTX is a promising candidate for further in vivo evaluation as an intranasal formulation for glioblastoma treatment and Cytotoxicity assays showed that HNP–PTX reduced cell viability more than both taxol and temozolomide (TMZ).
Anna Carolina da Silva Sousa, C. M. R. Oda, André Luís Branco de Barros et al.
· ACS Omega · 0 citations