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C. Manyumwa

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Open access Oct 2026

Comparative Characterization of α-Carbonic Anhydrases from Bacteria Aeromonas hydrophila, Halomonas binhaiensis, and Roseibium salinum: Insights into Halotolerance and Thermostability

Halotolerant enzymes are promising biocatalysts for industrial applications due to their ability to function under high salinity and temperature conditions that typically inactivate conventional enzymes. This is particularly relevant for biomineralization-based carbon capture, where carbonic anhydrases (CAs) catalyze t...

Isabella del Furia, Nina Gehres Dietz, Carsten Jers et al. · 0 citations
Open access Aug 2026

Engineering of a Carbonic Anhydrase from Hydrogenimonas thermophila Through Fusion Tags and Surface Mutagenesis Enhances Solubility While Revealing Stability–Function Relationships

Protein solubility can limit enzyme performance in industrial applications. This is the case for some carbonic anhydrases (CAs), key enzymes for CO2 capture and utilization. In this study, we investigated an α-class CA from the thermophilic bacterium Hydrogenimonas thermophila (HtCA), which was predominantly expressed...

C. Manyumwa, Carsten Jers, Ivan Mijakovic · 0 citations

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