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Author

C. Maurange

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Open access Aug 2026

MYCN-induced lineage infidelity initiates SHH medulloblastoma-like tumors outside the canonical lineage of origin

This work combines the experimental accessibility of the avian embryo with single-cell transcriptomics to investigate how MYCN overexpression reshapes cerebellar lineage trajectories and reveals that MYCN-induced oncogenicity in the cerebellum proceeds through a three-step temporal sequence driven by the erosion of lin...

Lauranne Bouteille, William Fargues, Paul de Boissier et al. · 0 citations

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