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C. Middeldorp

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Open access Oct 2026

Association between polygenic liability to depression and lifetime depression in at-risk adolescents.

Internalising symptoms including depression, anxiety and somatic symptoms in adolescence are common. They can be transient, but they can also persist and progress to major depressive disorder (MDD) Polygenic risk scores for major depression (MD-PGS) may help identify which symptomatic adolescents are at greatest risk o...

E. Byrne, Nathan A. Gillespie, J. Najman et al. · 0 citations
Open access Sep 2026

Genome-wide analysis of social behaviour across social domains, reporters and developmental stages: a meta-regression approach.

Social behaviour is a heritable trait linked to well-being and mental health, yet it varies across social context, including social domains, informants and development, which may shape its underlying genomic architecture. Here, we conducted a genome-wide meta-regression meta-analysis of social behaviour from infancy to...

L. de Hoyos, Fenja Schlag, Sanjeevan Jahagirdar et al. · 0 citations
Open access Aug 2026

Association between menstrual cycle characteristics and mental health in early adolescence.

The association between irregular cycles and depression, and between long cycles and depression and anxiety, strengthened significantly with increasing gynaecologic age, while symptom burden associations were consistent throughout the post-menarcheal period.

Sushma Marla, S. Gangaraju, Josh Nguyen et al. · 0 citations

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