Author

C. Mikkelsen

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Open access Aug 2026

Genetic architecture of cytokine autoantibodies and associated risk of common diseases

Anti-cytokine autoantibodies are increasingly recognized as modulators of immune function and determinants of disease risk, yet their genetic basis and population-level impact remain unclear. Here we perform genome-wide association studies of autoantibodies against IL-1α, IL-6, IL-10, IFN-α, IFN-β, IFN-γ and GM-CSF in...

J. V. von Stemann, Joseph Dowsett, R. Teglgaard et al. · Nature Communications · 0 citations

Open access Jul 2026

Combining genome-wide polygenic scores with registry data for colorectal cancer risk-based screening.

Polygenic risk scores stratifies lifetime adenoma and CRC risk and may inform risk-based screening initiation and intensity but adds limited predictive value when combined with FIT.

A. Nøhr, M. G. Overby, M. Nielsen et al. · British Journal of Cancer · 0 citations

Open access Jul 2026

Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders

BPD showed the strongest positive genetic correlations with GWAS of post-traumatic stress disorder, depression, attention deficit hyperactivity disorder, antisocial behavior, antisocial behavior, and measures of suicide and self-harm.

F. Streit, S. Awasthi, Alisha S. M. Hall et al. · Nature Genetics · 1 citation