Author

C. Moiola

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Open access Jul 2026

Combinatorial MAPK states drive opposing gene programmes: a reanalysis of MAP3K-driven transcriptional responses in MCF10A cells

It is demonstrated that MAP3Ks co-activating ERK and JNK drive approximately tenfold more cell cycle entry than MAP3Ks activating ERK alone, and that both kinase activities are independently required for this proliferative response.

M. Solé, Beatriz Candás-Estébanez, R. K. da Palma et al. · bioRxiv · 0 citations