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C. N. Miller

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Open access Sep 2026

CaMKII monomers are sufficient for GluN2B binding, co-condensation, and synaptic potentiation

SUMMARY Cognitive functions require synaptic plasticity, specifically long-term potentiation (LTP). LTP is thought to require CaMKII binding to the NMDA-type glutamate receptor subunit GluN2B, but this poses a conundrum: Truncated CaMKII monomers (without the hub domain that forms 12meric holoenzymes) fail to bind GluN...

Carolyn Nicole Brown, C. M. Barker, C. N. Miller et al. · 0 citations

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