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Author

C. Pearce

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Open access Sep 2026

Electrophilic aromatic halogenation of perylenequinones: a strategy to improve photodynamic properties.

Halogen substitution is a widely used strategy in medicinal chemistry to modulate the physicochemical and biological properties of drug candidates. Here, we report the electrophilic aromatic halogenation of two fungal perylenequinones, ent-shiraiachrome A (1) and hypocrellin B (2), using N-halosuccinimides, where the r...

Reema A. Al-Qiam, Ge Shi, C. Pearce et al. · 0 citations

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