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Author

C. Queiroz-Junior

3 papers indexed here

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Aug 2026

Pre-clinical evaluation of (2E,5E)-2,5-bis(isoquinolin-5-ylmethylene)-cyclopentanone as a promising leishmanicidal agent.

Leishmaniasis is a neglected tropical disease whose current treatments present several limitations. In this context, the search for new antileishmanial agents remains highly relevant. The aim of this study was to investigate the safety and therapeutic potential of (2E,5E)-2,5-bis(isoquinolin-5-ylmethylene)cyclopentanon...

Isabela Cristina Soares Martins, T. T. Santos, C. Queiroz-Junior et al. · 0 citations
Jul 2026

A Phytotherapeutic Candidate for Neuropathic Pain: Helicteres ovata (Lam.) Extract Shows Antinociceptive Effects and Favorable Acute Toxicity Profile.

ETHNOPHARMACOLOGICAL RELEVANCE Helicteres ovata is a native Brazilian species belonging to a genus traditionally used for the treatment of inflammatory and pain-related disorders. However, its pharmacological studies remain scarce. AIM OF THE STUDY This study investigated the phytochemical profile, inorganic composit...

R. C. de Matos, A. F. A. Bitencourt, Pedro Augusto Lemos Santana et al. · 0 citations
Jul 2026

Adoptive transfer of interleukin-4 programmed macrophages reduces lung inflammation during betacoronavirus infection.

Systemic delivery of M(IL4) attenuated MHV-A59-induced inflammatory responses, as evidenced by reduced pro-inflammatory cytokine levels, decreased lung tissue damage, and enhanced viral clearance and pave the way for further investigation of macrophages as therapy for individuals with severe cases of respiratory viral...

F. B. Felix, V. A. Beltrami, Ana Paula Soares da Cruz Maravilha et al. · 0 citations

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