Cognitive components derived from traditional neuropsychological tests and their associations with plasma p-tau217 and p-tau181 in mild cognitive impairment: a multisite analysis.
The findings indicate that a robust four-factor cognitive structure can be identified in clinically defined MCI cohorts without prior biological selection, and the association between latent memory factors and plasma p-tau217, observed primarily in cohorts with higher biomarker burden or clearer amnestic profiles, high...