Open access
Sep 2026
The diadenosine tetraphosphate hydrolase YqeK controls fitness, biofilm formation, staphyloxanthin production and virulence in Staphylococcus aureus
It is shown that AP4A is upregulated upon deletion of yqeK encoding the Ap4A hydrolase in S. aureus COL, and the ΔyqeK mutant was impaired in growth and survival during oxidative stress and after infection of murine macrophages, indicating that Ap4A contributes to the host-pathogen interactions in S. aureus.
Loi Van Vu, Sarah Przibilla, Fabiana Burchert et al.
· bioRxiv · 0 citations