Author

C. Sakulthaew

2 papers indexed here

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Open access Aug 2026

Oxidative Stress-Mediated Mitochondrial Dysfunction Drives Genistein-Induced Apoptosis in TM4 Sertoli and ELT3 Leiomyoma Cells

Genistein (GEN) exhibits concentration- and cell-type-dependent biological activities; however, the mechanisms underlying its cytotoxicity remain incompletely understood. This study investigated whether oxidative stress-mediated mitochondrial dysfunction contributes to GEN-induced apoptosis in TM4 mouse Sertoli cells a...

Samak Sutjarit, C. Sakulthaew, Nattakan Meekhanon et al. · Journal of Xenobiotics · 0 citations

Open access Jul 2026

Redox-mediated mitochondrial collapse drives intrinsic apoptotic signaling in ELT3 cells response to apigenin

Uterine leiomyoma is the most common benign gynecological tumor and a major cause of abnormal uterine bleeding, pelvic pain, and infertility. Although apigenin (API) exhibits antioxidant, antiproliferative, and anticancer activities, its mechanism of action in uterine leiomyoma, particularly the involvement of oxidativ...

Samak Sutjarit, C. Setthawongsin, C. Sakulthaew et al. · Toxicology Reports · 0 citations