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Author

C. Salée

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Open access Aug 2026

NKCC1 as a regulator of stemness and redox balance in colorectal cancer

Na⁺-K⁺-2Cl − cotransporter 1 (encoded by SLC12A2 ) is a solute carrier overexpressed in colorectal cancer (CRC), but its functional role remains unclear. Here, we identify NKCC1 as a marker of normal intestinal stem cells, supported by its crypt-base localization, single-cell transcriptomics, and patient-derive...

P. Adam, C. Salée, Pauline Bomboire et al. · 0 citations

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