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C. Scheele

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Open access Oct 2026

Functional Mammary Gland Organoids From Human Induced Pluripotent Stem Cells

The human mammary gland arises through sequential lineage restrictions from surface ectoderm to hormone-responsive bilayered epithelium, yet a tractable in vitro model that captures these events has remained elusive. Here, we established a stepwise differentiation protocol that directs human induced pluripotent stem ce...

Roshni Nair, Maarten Ganne, Larissa Mourão et al. · 0 citations

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