Oct 2026
Second coordination sphere controls structural flexibility of blue copper protein: A basis for entatic state formation.
Metalloproteins exhibit remarkable reactivity through the precise tuning of metal active sites embedded in the protein matrix. The concepts of the entatic state and rack-induced bonding describe how protein-imposed constraints optimize the metal-coordination structure for physiological functions. Blue copper proteins (...
Shota Hashimoto, Takahide Yamaguchi, Nao Ishikawa et al.
· Journal of Inorganic Biochem... · 0 citations