Bone microarchitecture and microfractures in disorganized bone in a young female with pycnodysostosis and atypical femur fractures: A case for novel fracture prediction technology using ALIGNOGRAM1.0 analysis.
Pycnodysostosis (PYCD) is a rare genetic bone disease characterized by impaired osteoclastic bone resorption. The inability to resorb bone leads to sclerosis, with increased bone mineral density (BMD) but paradoxically increased bone fragility. We report a case of a young female with PYCD with multiple fragility fractu...