Desmoplastic/nodular medulloblastoma (DNMB) is a histologically and molecularly distinct variant of a common pediatric embryonal brain tumor. DNMB is disproportionately represented among Sonic Hedgehog (SHH)-activated tumors in infants and very young children. When it is TP53-wildtype, a comparatively favorable prognos...
Jala El-Biali, Andressa Balbi, Leander Galan et al.· World Journal of Advanced Re...· 0 citations
Pulmonary pleomorphic carcinoma (PPC) is a rare subtype of pulmonary sarcomatoid carcinoma (PSC) within the non-small cell lung cancer category, characterized by significant histological heterogeneity that complicates diagnosis. A 71-year-old male with a 55-pack-year smoking history and chronic obstructive pulmonary di...
Marcos Domínguez, J. Viera, C. Steinman et al.· World Journal of Advanced Re...· 0 citations
The spindle cell subtype of medullary thyroid carcinoma (MTC) is an exceptionally rare morphologic pattern that can be mistaken cytologically and histologically for anaplastic thyroid carcinoma, sarcoma, melanoma, and other spindle cell lesions of the neck, creating a substantial diagnostic pitfall. We report a 72-year...
C. Steinman, Sean Rockwell, Karen Sanabria et al.· World Journal of Biology Pha...· 0 citations
This case illustrates how a decade-long latency, mixed histomorphology, and a high-risk molecular profile can complicate the recognition of anaplastic transformation, and underscores the diagnostic and therapeutic pathway required for optimal management.
G. Durham, Cindy Almaraz, C. Steinman et al.· World Journal of Biology Pha...· 0 citations
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