Author

C. Thålin

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Open access Aug 2026

Vaccination-first immune priming shapes a sustained mRNA vaccine-induced IgG4 class switch that associates with SARS-CoV-2 breakthrough infection risk

The results illustrate an IgG4-dominated immunological signature in both adults and children and highlight that immune priming by prior infection may shape subsequent mRNA vaccine-induced antibody responses.

T. Pongrácz, U. Marking, O. Bladh et al. · Scientific Reports · 0 citations