Open access
2026
Method for Analyzing Nucleoskeletal Components from the Isolated Nucleus.
Marina Armesto, C. Toseland, Javier Redondo-Muñoz
· Methods in molecular biology · 0 citations
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Open access
Sep 2026
Nuclear Myosin VI stabilises Ku-associated DNA ends during nonhomologous end joining
DNA double-strand breaks (DSBs) require rapid signalling and physical stabilisation of broken DNA ends to preserve genome integrity. Here, we identify myosin VI (MVI) as an ATM-regulated component of the DSB response. DNA damage induces rapid nuclear accumulation and nanoscale reorganisation of MVI across multiple cell...
Abdulmohsen Alanazi, Alexander W. Cook, Isabel W. Shahid-Fuente et al.
· bioRxiv · 0 citations
Open access
Aug 2026
An integrin beta-1-anchored bicaudal C1-polycystin-1 module essential for tubular morphogenesis in polycystic kidney disease
Findings reveal a novel model of cystogenesis linking BICC1’s dual RNA and protein regulatory functions to the maintenance of cytoskeletal and tubular integrity.
Andrew J. Streets, Manoj K. Valluru, Devon Smith et al.
· iScience · 0 citations