Open access
Sep 2026
The Alzheimer's disease risk gene SORL1 is a regulator of excitatory neuronal function
Synaptic dysfunction is an early feature of Alzheimer's disease (AD) and proper localization of proteins involved in pre‐ and post‐synaptic composition is dependent on endosomal recycling and trafficking, cellular processes involving the AD risk gene sortilin‐related receptor 1 (SORL1).
C. Williams, Shannon E. Rose, Vera Stamenković et al.
· Alzheimer's & Dementia · 0 citations