The different neurological characteristics of "psycho" and "motor" retardation in depression: A perspective from the subdivision of the striatum.
Psychomotor retardation (PMR) is a core feature of major depressive disorder (MDD), yet its neural substrates remain elusive. We hypothesized that aberrant striato-cortical connectivity differentially underlies the cognitive and motor components of PMR. In a case-control study, 172 PMR patients, 387 non-PMR patients, a...