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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

C. Yu

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Open access Sep 2026

Single Amino Acid Disease Mutations Act as Genetic Glues to Drive Neo-substrate Degradation

Disease-associated missense mutations are well known to affect protein turnover by either impairing substrate-ubiquitin ligase interactions or inducing misfolding-triggered protein clearance. Whether such mutations can drive gain-of-function in substrate-selective protein degradation remains under-explored. Here, we de...

Bai-Yun Wang, Chi-Wei Yeh, Hsuan-Mei Lin et al. · 0 citations
Open access Aug 2026

A dominant mutation in tomato DNA POLYMERASE DELTA 1 causes geminivirus DNA replication catastrophe

The mutant POLD1 enzyme reported here introduces mutations into the viral genome during replication, thereby disrupting the function of essential viral proteins, and is a powerful resistance mechanism that plant geminiviruses cannot escape.

Deri Gustian, C. Yu, F. Jan et al. · 0 citations

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