Cai-Ling Fan

Zinc-mediated rigid cyclization enables highly enantioselective fluorescent recognition of chiral amino alcohols in aqueous phase.

Chiral amino alcohols represent a crucial class of chiral amines with significant applications across various fields. Herein, a novel BINOL-based fluorescent probe(R)-5, featuring dual aldehyde and hydroxyl functionalities, was rationally designed and synthesized. (R)-5 exhibited excellent enantioselective recognition...