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Author

Cailu Song

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Review Open access Aug 2026

The role of fumarate and itaconate in tumor microenvironment.

The oncogenic mechanisms of fumarate and itaconate are summarized, viable strategies to address technical hurdles in studying non-enzymatic protein modifications are proposed and new directions for the clinical treatment of tumors are offered through targeted inhibition of fumarate and itaconate.

Yi-Dan Fan, Han-Qiu Zhang, Jinkun Qin et al. · 0 citations
Open access Jul 2026

Single-cell sequencing profiling of intratumoral heterogeneity and immunosuppressive microenvironment in primary thyroid cancer and lymph node metastases

This study comprehensively maps the coevolution of malignant thyrocyte plasticity and the immunosuppressive metastatic niche in thyroid cancer and provides a robust molecular rationale for developing next-generation immunotherapeutic strategies tailored to thyroid cancer.

Shu-hang Xu, Yaorong Su, Senmin Zhang et al. · 0 citations

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