Open access
Aug 2026
Genetic and pharmaceutical targeting of Suv39h1 ameliorates renal fibrosis by unlocking CXCL10 transcription.
A critical role for the lysine methyltransferase Suv39h1 in regulating fibroblast-myofibroblast transition (FMyT) and renal fibrosis is identified and Suv39h1-mediated regulation as a previously unrecognized facet of renal fibrogenesis is identified.
Xiao-Yan Wu, Ya-Jun Luo, Caiyi Wu et al.
· Journal of Advanced Research · 0 citations