Lipid nanoparticles (LNPs) are a clinically validated nonviral platform for the delivery of CRISPR-associated components. Composed of ionizable lipids, phospholipids, cholesterol, and PEG-lipids, LNPs enable the efficient encapsulation, protection, and cytosolic delivery of therapeutic cargo such as DNA, RNA, or protei...
A. Olsen, Camilla Blunk Brandt, Rasmus Karred Larsen et al.· Methods in molecular biology· 0 citations
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