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Author

Camille Le Drezen

2 papers indexed here

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Open access Sep 2026

Distinct atypical chemokine receptor 1 determinants underlie bacterial toxins recognition and pore formation

Atypical chemokine receptor 1 (ACKR1) is one of the most promiscuous receptors in the human chemokine system, engaging structurally diverse chemokines through a conformationally flexible N-terminal tail. This same interface is exploited by pathogens, including Plasmodium vivax and Staphylococcus aureus (SA), via a comp...

A. Fouillen, Élodie Logerot, Zainab Ammar et al. · 0 citations
Open access Jul 2026

Machine Learning-Guided Engineering of High-Affinity Cross-Reactive Antibodies with Minimal Mutations

A Deep Mutational Scanning-coupled deep learning strategy to engineer potent cross-reactive antibodies with minimal sequence divergence that retained PD-1/PD-L1 blockade and demonstrated therapeutic activity in a mouse tumor model is developed.

H. Dorison, Anne-Laure Grindel, François Thenier et al. · 0 citations

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