Author

Can Li

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Jul 2026

CLOCK confers EGFR-TKIs resistance in non-small cell lung cancer by transcriptionally upregulating LAMC2 expression and activating multiple kinase signaling.

Findings for the first time identify CLOCK as a critical mediator of EGFR-TKIs resistance and a promising target to overcome EGFR-TKIs resistance in NSCLC.

Yan-Kang Li, Lin-Yu Han, Hui-Wen Luan et al. · Archives of Biochemistry and... · 0 citations