Open access
Sep 2026
Interferome profiling in the blood links IFNα5-Mucin-1 axis to HIV-1 pathogenesis
ABSTRACT Type I interferons (IFN-Is) are essential for antiviral immunity, but contribute to immune dysfunction during chronic HIV-1 infection. IFN-Is comprise multiple IFNα subtypes that signal through a common receptor yet exhibit distinct biological activities, but their qualitative roles in HIV-1 pathogenesis remai...
Ke-Jun Guo, Stephanie M. Dillon, Emily Meneses et al.
· Journal of Virology · 0 citations