Open access
Sep 2026
Post-transcriptional regulation maintains neurogenic potential of human neural progenitor cells.
Increasing evidence supports important roles of post-transcriptional regulation in brain development; however, the precise mechanism remains unclear. Here, we show that Fragile X autosomal homolog 1 (FXR1), a brain-enriched RNA-binding protein (RBP), is essential for human neurogenesis. FXR1-deficient human cortical ne...
Natasha M. Méndez-Albelo, Ya-Jie Zhang, Soraya O. Sandoval et al.
· Stem Cell Reports · 0 citations