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Author

Carla L. Coackley

1 paper indexed here

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Sep 2026

Electrostatic Regulation of Alpha-Synuclein Membrane Binding Couples Conformational Release to Aggregation Kinetics

Misfolding and aggregation of α-synuclein (α-syn) are central to Parkinson’s disease (PD) pathology and are increasingly believed to be modulated by lipid-rich cellular environments. Electrostatic interactions between α-syn and anionic lipids play a key role in membrane binding and can significantly influence aggrega...

Mahdi Lavasani, Ping Lu, Shehani V. Siripala et al. · 0 citations

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