Open access
Aug 2026
Comparative Single-Cell Profiling of CRISPR Knockout and Interference Defines Modality-Specific Strengths in Functional Genomics
While CRISPRi allows direct assessment of target gene repression, CRISPRko provides an effective complementary approach for complete loss-of-function studies, expanding the toolkit for single-cell functional genomics.
Nikhil Gupta, Andrew Sayer, Malwina Prater et al.
· bioRxiv · 0 citations