Jul 2026
Allograft Inflammatory Factor 1 expression in cDC1 is required to direct Tbet—driven T cell immunity to defend against intracellular pathogens in vivo 2256292
Findings identify AIF1 as a critical regulator of cDC1 immunogenic identity and protective T cell immunity to intracellular infection, defining a pathway where AIF1 loss reprograms DC—T cell communication toward a regulatory, non-protective outcome.
Lais Rekowsky, Ricardo L. L. da Silva, Jonathan A. Seenarine et al.
· Journal of Immunology · 0 citations