Resistance training prevents the development of sarcopenia induced by chronic cholestatic liver disease
Sarcopenia secondary to chronic cholestatic liver disease (CCLD) is linked to activation of the ubiquitin-proteasome system (UPS) and autophagy-lysosome system (ALS), impaired mitochondrial dynamics, and diminished mTOR signaling. Resistance training (RT) has shown benefits against age-related sarcopenia, but its effec...