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Carolina Mangana

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Open access Jul 2026

RIPPLE: replicate-aware detection of cell-type-anchored proximity gradients in spatial transcriptomics

RIPPLE (Replicate-Aware Inference of Paracrine Profiles via Likelihood Estimation), an R package that takes a query cell type and scans all other cell types for genes whose expression varies with distance to it, delivers ranked, cell-type-resolved paracrine candidates for experimental follow-up.

Carolina Mangana, Barbara B. Maier · 0 citations

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