The management of glaucoma with drugs is mostly via the topical route, although these treatments have poor ocular bioavailability. Other problems limiting their therapeutic effect include pre-corneal clearance, corneal and ocular surface barriers, and the need for a long-term treatment regimen. Nanoparticle-mediated dr...
Matteo Capobianco, Marco Zeppieri, M. L. Salvetat et al.· Pharmaceuticals· 0 citations
Worse peripheral hearing was associated with poorer unadjusted gait performance in cognitively unimpaired adults and apparent sex differences did not reach the prespecified threshold.
Federico Mollame, A. Maniaci, Francesco Pegreffi et al.· The Laryngoscope· 0 citations
The development and validation of robust OCT-based biomarkers have the potential to enable earlier diagnosis, improved disease monitoring, and personalised treatment strategies, and future research that integrates quantitative imaging, computational analysis, and longitudinal clinical data will be essential to fully re...
Lan-Xing Fu, Y. Luo, Nick Kopsachilis et al.· Diseases· 0 citations
The capacity of TSI to deliver lutein inside the retina, overcoming physiological barriers that may limit the efficacy of lutein oral administration is highlighted, overcoming physiological barriers that may limit the efficacy of lutein oral administration.
M. L. Salvetat, Francesco Pellegrini, Marco Zeppieri et al.· Diseases· 0 citations
The limits of using high-performing artificial intelligence systems in ocular image processing, which seldom lead to enhanced patient outcomes, are assessed and the scientific, clinical, and practical techniques required to close this gap are delineated.
Marco Zeppieri, Matteo Capobianco, Federico Visalli et al.· World Journal of Methodology· 0 citations
Artificial intelligence in ophthalmology encounters a continual challenge: Systems proficient in picture classification seldom yield quantifiable enhancements in patient outcomes. The primary concern is the disparity between pixel-level performance metrics and their clinical significance. Primary obstacles encompass da...
Marco Zeppieri, Matteo Capobianco, Federico Visalli et al.· World Journal of Methodology· 0 citations
The mitochondrial, redox, inflammatory, and neurovascular mechanisms proposed for PBM are examined, and preclinical and clinical evidence across nonexudative AMD, inherited retinal degeneration, diabetic retinal disease, and light-induced damage is discussed.
M. Toro, Alessandro Avitabile, Roberta Amato et al.· Antioxidants· 0 citations
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