Sep 2026
Age-related emergence of behavioral deficits and amyloid pathology in the J20 mouse model of Alzheimer's disease.
Transgenic mouse models carrying familial Alzheimer's disease mutations are widely used in preclinical research, yet phenotypic variability across age and sex can complicate experimental design and interpretation. Here, we performed an age-stratified behavioral and pathological phenotyping of the hAPP-J20 mouse model u...
Geoffrey Canet, C. Zussy, Léa Otaegui et al.
· Behavioural Brain Research · 0 citations