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Cathleen M. Lutz

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Open access Sep 2026

Neurodegeneration and inflammation in a novel spinocerebellar ataxia 13 preclinical model

Neuroinflammation is a critical pathological feature underlying neurodegenerative diseases. Spinocerebellar ataxia 13 (SCA13) is a heterogeneous ataxia with several allelic variations of differing phenotypes. All are neurodegenerative and currently without effective treatment. Our prior work identified human KCNC3...

Jun-Xiang Yin, Michael Wu, Jennifer White et al. · 0 citations
Review Open access Aug 2026

Childhood-Onset Neurodegeneration and Brain Atrophy: Defining UBTF-Related Developmental Regression and Progressive Ataxia

UBTF-related CONDBA presents with early normal or mildly delayed development followed by regression and progressive ataxia, and elevated NFL may serve as a biomarker of neuronal injury in both humans and animal models.

A. Nagy, A. Luddy, Francine Molay et al. · 0 citations

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