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Author

Cathrine Sant

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Open access Aug 2026

Tau reduction counteracts transcriptomic and behavioral abnormalities in an Alzheimer amyloid model

Tau reduction supports the potential benefits and safety of overall tau reduction and the hypothesis that even physiological forms of tau can allow pathogenic triggers such as AD-mutant APP and PS1 to elicit aberrant neuronal activities and synaptic degeneration.

Sara J. Knowles, Cathrine Sant, Pranav Nambiar et al. · 0 citations

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