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Open access
Oct 2026
An integrated workflow for real-time chemoenzymatic CMP-sialic acid preparation and a bioorthogonal microplate sialyltransferase assay (MPSA)
Abstract Sialylation at the terminal ends of cell-surface glycoproteins and glycolipids plays a pivotal role in dictating cellular interactions, human health, and pathological processes. This crucial modification is mediated by a family of 20 distinct human sialyltransferases (STs) whose exquisite substrate specificiti...
Lucas Lancel, Sushmaa Dangudubiyyam, Clémence Simon et al.
· Biology Methods and Protocol... · 0 citations